SIRT2 inhibitor

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Catalog No. A14225

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AGK2 10mg A14225-10
AGK2 25mg A14225-25
AGK2 50mg A14225-50
AGK2 10mM * 1mL in DMSO A14225-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM.


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Chemical Information

Catalog Num A14225
Actions Inhibitor
M. Wt 434.27
Formula C23H13Cl2N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 304896-28-4
Synonyms AGK 2
SMILES code C1=CC2=C(C=CC=N2)C(=C1)NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/C#N
Chemical Name 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide

Biological Activity

AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM.
3.5 μM


Solubility (25°C)* In vitro DMSO 10 mg/mL heating (23.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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