APS-2-79 HCl

Catalog No.: A16175
KSR/Ras inhibitor
APS-2-79 HCl, small molecule that stabilizes the KSR (Kinase suppressor of Ras) inactive state and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2).
Grouped product items
Product Name Price Stock Qty
APS-2-79 HCl 5mg
$45.00
In stock
APS-2-79 HCl 10mg
$65.00
In stock
APS-2-79 HCl 50mg
$210.00
In stock
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Biological Activity
Discription APS-2-79 HCl, small molecule that stabilizes the KSR (Kinase suppressor of Ras) inactive state and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2).
Targets
Target Value
Product Information
Catalog Num A16175
Formula C23H21N3O3.HCl
Molecular Weight 423.89
CAS Number 2002381-31-7
SMILES CC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl
Synonyms KSR/Ras Inhibitor
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 82 mg/mL (193.44 mM)
Water Insoluble
Ethanol 27 mg/mL (63.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.59 mL 117.96 mL 235.91 mL
0.5 mM 4.72 mL 23.59 mL 47.18 mL
1 mM 2.36 mL 11.8 mL 23.59 mL
5 mM 0.47 mL 2.36 mL 4.72 mL
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