APS-2-79 HCl
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | APS-2-79 HCl, small molecule that stabilizes the KSR (Kinase suppressor of Ras) inactive state and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2). | ||
---|---|---|---|
Targets |
|
Catalog Num | A16175 |
---|---|
Formula | C23H21N3O3.HCl |
Molecular Weight | 423.89 |
CAS Number | 2002381-31-7 |
SMILES | CC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl |
Synonyms | KSR/Ras Inhibitor |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 82 mg/mL (193.44 mM) | |
Water | Insoluble | ||
Ethanol | 27 mg/mL (63.69 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.59 mL | 117.96 mL | 235.91 mL |
0.5 mM | 4.72 mL | 23.59 mL | 47.18 mL |
1 mM | 2.36 mL | 11.8 mL | 23.59 mL |
5 mM | 0.47 mL | 2.36 mL | 4.72 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2