Autophagy

Target
  1. Autophagy (1)
Actions
  1. Activator (1)
  2. Inducer (1)
  3. Inhibitor (3)


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Catalog No. Product Name Application Product Information
A15868

PIK-III

Autophagy Inhibitor
PIK-III is a selective inhibitor of ?VPS34 enzymatic activity.
A15795

SBI-0206965

ULK1 inhibitor
SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .
A15867

SMER28

Autophagy Activator
SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells.
A12942

Spautin-1

Autophagy Inhibitor
Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03??M. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 uM.
A10866

STF-62247

Autophagy Inducer
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).

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