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BIBX1382

EGFR inhibitor

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Catalog No. A15531

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BIBX1382 5mg A15531-5
$75.00
BIBX1382 10mg A15531-10
$120.00
BIBX1382 25mg A15531-25
$250.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BIBX1382 is a potent, selective inhibitor of EGFR tyrosine kinase (IC50 = 3 nM); displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 _mu_M) and a range of other related tyrosine kinases (IC50 > 10 _mu_M),

BIBX1382

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Chemical Information

Catalog Num A15531
Actions Inhibitor
M. Wt 387.84
Formula C18H19ClFN7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 96612-93-8
Synonyms Falnidamol, BIBX-1382, BIBX 1382
SMILES code CN1CCC(CC1)NC2=NC=C3C(=N2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl
Chemical Name 4-N-(3-chloro-4-fluorophenyl)-6-N-(1-methylpiperidin-4-yl)pyrimido[5,4-d]pyrimidine-4,6-diamine

Biological Activity

Description
BIBX1382 is a potent, selective inhibitor of EGFR tyrosine kinase (IC50 = 3 nM); displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 _mu_M) and a range of other related tyrosine kinases (IC50 > 10 _mu_M),

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