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Catalog No. Product Name Application Product Information
A12729 SALE


BET Inhibitor
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.
A14160 SALE


BET bromodomain inhibitor
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes.


BAZ2 bromodomain inhibitor
BAZ2-ICR is an excellent chemical probe for functional studies of the BAZ2 bromodomains in vitro and in vivo.


BRD9 BD Inhibitor
BI-7273 is a selective, and cell-permeable BRD9 BD inhibitor.
A16196 SALE


BRD7/9 inhibitor
BI-9564 is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14.1 and 239 nM; IC50s = 75 nM and 3.4 uM, respectively).
A13163 SALE


bromodomain inhibitor
Bromosporine is a broad spectrum inhibitor for bromodomains with IC50 of 0.41 ??M, 0.29 ??M, 0.122 ??M and 0.017 ??M for BRD2, BRD4, BRD9 and CECR2, respectively.

CPI 0610

BET bromodomain inhibitor
CPI 0610 is a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity.


BET bromodomain Inhibitor
CPI203 is a novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 with an IC50 of ~37 nM (BRD4 α-screen assay).
A11783 SALE

GSK 1210151A (I-BET151)

BET Bromodomain Inhibitor
GSK1210151A is a novel selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4.
A11440 SALE

GSK 525762A (I-BET-762)

BET inhibitor
GSK-525762A is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family

GSK 525768A

BET bromodomain inhibitor
GSK 525768A is the enantiomer compound of GSK 525762A(HY-13032, which is a potent small molecule inhibitor that disrupt the function of the BET family of bromodomains (Brd2, Brd3, and Brd4); GSK 525768A has NO activity towards BET.

GSK 5959

BRPF1 bromodomain inhibitor
GSK 5959 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with IC50 ~ 80 nM. Exhibits >100-fold selectivity for BRPF1 over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains.
A14015 SALE


BAZ2A and BAZ2B inhibitor
GSK2801 is a very potent inhibitor of the BAZ2 family of bromodomain containing proteins


Selective BRD9 inhibitor
I-BRD9 is a potent and selective BRD9 inhibitor with pIC50 of 7.3, while it displayed a pIC50 of 5.3 against BRD4.
A13165 SALE


CBP/p300 bromodomain inhibitor
I-CBP112 is a highly potent and selective p300/CBP bromodomain inhibitor (IC50 ~0.14-0.17 uM for CBP and ~0.625 uM for p300).


BRD4 inhibitor
MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.
A13890 SALE


BET inhibitor
OTX015 is an orally bioavailable, small molecule inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10-19 nM).


BRPF1 bromodomain inhibitor
PFI-4 is a potent and selective and cell permeable BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4.
A12545 SALE


BET inhibitor
PFI-1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4.
A13956 SALE


BET bromodomain inhibitor
RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 ??M for BD2, about 170-fold selectivity over BD1.


Pan PI3K inhibitor
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.


CBP/p300 bromodomain inhibitor
SGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are general transcriptional co-activators.

UNC 669

L3MBTL inhibitor
UNC669 is a small-molecule antagonist of methyl-lysine (KMe) reader protein with selectivity for L3MBTL1 and L3MBTL3 (IC50 of 4.2μM and 3.1μM respectively)
A12948 SALE


L3MBTL3 inhibitor
UNC1215 is a potent, selective antagonist of L3MBTL3 with cellular activity.

24 Item(s)

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