Carbonic Anhydrase

Inhibitory Selectivity
Catalog No.Inhibitor Name Carbonic AnhydraseCarbonic Anhydrase ICarbonic Anhydrase IICarbonic Anhydrase IVCarbonic Anhydrase IXCarbonic Anhydrase XII
A10333Dorzolamide HCl
*
****
***
A14959U-104
*
*
**
****
A11673Tioxolone
**
A11765Brinzolamide
****
***
A10303Dichlorphenamide
A15859Acetazolamide
***
A13594Benzenesulfonamide

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.



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Catalog No. Product Name Application Product Information
A10333

Dorzolamide HCL

carbonic anhydrase inhibitor
Dorzolamide HCl is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide HCl is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
A15859

Acetazolamide

Carbonic Anhydrase Inhibitor
Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).
A14959

U-104

Carbonic anhydrase (CA) inhibitor
U-104 is a novel ureido-sulfonamide inhibitor of Carbonic Anhydrase IX (CAIX).
A14410

DTP348

CAIX inhibitor/ radiosensitizer
DTP348 is an oral dual CAIX inhibitor/ radiosensitizer.
A12106

Punicalin

Carbonic anhydrase inhibitor
Punicalin is a highly active carbonic anhydrase inhibitor.
A12105

Punicalagin

Carbonic anhydrase inhibitor
Punicalagin is an ellagitannin, a type of phenolic compounds. It is a highly active carbonic anhydrase inhibitor.
A12325 SALE

Indisulam (E7070)

Carbonic anhydrase inhbitor
Indisulam (E7070) is a carbonic anhydrase inhbitor, is also a novel synthetic sulfon-amide that targets the G1 phase of the cell cycle.
A10303

Diclofenamide

Carbonic anhydrase inhibitor
Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
A11765 SALE

Brinzolamide

Carbonic anhydrase inhibitor
Brinzolamide is a carbonic anhydrase inhibitor.
A11673 SALE

Tioxolone

Carbonic anhydrase inhibitor
Tioxolone is an anti-acne preparation.
A13594

Benzenesulfonamide

Carbonic anhydrase inhibitor
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.

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