CFTR



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Catalog No. Product Name Application Product Information
A13723 SALE

CFTR-Inhibitor-II

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CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 uM).
A13511

IOWH032

CFTR inhibitor
IOWH032 is a CFTR inhibitor.
A15843 SALE

KM 11060

F508del-CFTR trafficking corrector
KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity
A10675 SALE

Oridonin (Isodonol)

CFTR Inhibitor
Oridonin (Isodonol), an entkaurane diterpenoid isolated from Rabdosia rubescens, is an important traditional Chinese herbal remedy.
A13000 SALE

PPQ-102

CFTR chloride channel inhibitor
PPQ-102 is a compound that targets intracellular nucleotide binding domain(s) of CFTR and inhibits CFTR- mediated chloride current in a voltage-dependent and reversible manner.
A10758 SALE

PTC124 (Ataluren)

CFTR inhibitor
PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
A12519

VX-661

CFTR corrector
VX-661 is another cystic fibrosis transmembrane conductance regulator (CFTR) corrector in development for the treatment of cystic fibrosis.
A10985 SALE

VX-770 (Ivacaftor)

CFTR activator
VX-770 (Ivacaftor) is known as a CFTR potentiator.
A10986 SALE

VX-809 (Lumacaftor)

CFTR modulator
VX-809 is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF).

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