CID-2858522

NF-κB inhibitor

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Catalog No. A15046

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CID-2858522 5mg A15046-5
$50.00
CID-2858522 10mg A15046-10
$90.00
CID-2858522 50mg A15046-50
$200.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.

CID-2858522

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Chemical Information

Catalog Num A15046
Actions Inhibitor
M. Wt 465.63
Formula C28H39N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 758679-97-9
Synonyms CID 2858522, CID2858522
SMILES code CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C
Chemical Name 1-(3,5-ditert-butyl-4-hydroxyphenyl)-2-[2-(3-hydroxypropylamino)-5,6-dimethylbenzimidazol-1-yl]ethanone

Biological Activity

Description
CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.

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