Cysteine protease

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Catalog No. Product Name Application Product Information

Acetyl-Calpastatin (184-210) (human)

Selective calpain inhibitor
Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid ??-protein (A??) 42, A??40 and A??42 ratio.
A12020 SALE


Cathepsin K inhibitor
Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys.


Cathepsin B inhibitor
A13593 SALE

CA-074 Methyl Ester

Cathepsin B inhibitor
CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.

Calpain Inhibitor II, ALLM

Calpain Inhibitor
Calpain Inhibitor II, ALLM is a cell-permeable inhibitor of calpain I, calpain II, cathepsin L and cathepsin B with Ki values of 120 nM, 230 nM, 0.6 nM and 100 nM, respectively.
A15295 SALE


Calpain inhibitor
Calpeptin is a cell permeable calpain inhibitor.

Cathepsin Inhibitor 1

Cathepsin Inhibitor
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
A13259 SALE

E 64d (Aloxistatin)

Cysteine Protease inhibitor
E-64d is an inhibitor of cathepsins B and L and it is lysosome and cell permeable.
A13257 SALE


Cysteine Protease inhibitor
E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
A15302 SALE

L 006235

Cathepsin K Inhibitor
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.

Loxistatin Acid (E64-C)

Cysteine Protease inhibitor
Loxistatin Acid, a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.

MDL 28170

Calpain Inhibitor III
MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.


Cysteine Protease inhibitor
MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
A11265 SALE

Odanacatib (MK-0822)

Cathepsin K Inhibitor
Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.
A15306 SALE

PD 150606

Non-peptide calpain inhibitor
PD 150606 is a cell-permeable, non-competitive, selective, non-peptide Ca2+ dependent calpain inhibitor for calpain-1 and for calpain-2 directed towards the Ca2+ binding sites of calpain.

PD 151746

Calpain inhibitor
PD 151746 is a selective, cell-permeable calpain inhibitor with Ki of 0.26 uM for μ-Calpain, about 20-fold selectivity over m-calpain.


Serine/cysteine protease inhibitor
PMSF is an irreversible serine/cysteine protease inhibitor.

SID 26681509

Human cathepsin L inhibitor
SID 26681509 is a reversible and potent human cathepsin L inhibitor. SID 26681509 displays no inhibitory activity of cathepsin G.


reversible Calpain inhibitor
SJA6017 is a cell permeable peptide aldehyde which functions as a reversible calpain inhibitor.


Cysteine protease inhibitor
Z-FA-FMK is an irreversible inhibitor of cysteine protease


Irreversible Cysteine Protease inhibitor
Z-FA-FMK is an irreversible cysteine protease inhibitor.

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