ABT-751 (E-7010)Catalog No. A10024

Quick Overview

ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.
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ABT-751 (E-7010)

Product Information
Catalog Num A10024
M. Wt 371.4
Formula C18H17N3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 141430-65-1
Synonyms ABT751
Chemical Name N-[2-[(4-Hydroxyphenyl)amino]-3-pyr idinyl]-4-methoxybenzenesulfonamide
SMILES Code COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O

Biological activity
Introduction
ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.
Targets
Microtubules
Solubility
Solubility (25C) * In vitro DMSO 74 mg/mL (199.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12 mg/mL (32.3 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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