CelecoxibCatalog No. A10193

Quick Overview

Celecoxib is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.

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Celecoxib

Product Information
Catalog Num A10193
M. Wt 381.4
Formula C17H14F3N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 169590-42-5
Synonyms Celebrex, Celebra
Chemical Name 4-[5-(4-methylphenyl)-3-(trifluoromethyl) pyrazol-1-yl]benzenesulfonamide
SMILES Code CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F

Biological activity
Introduction

Celecoxib is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.

Targets
COX-2 (Sf9 cells)
40 nM
Solubility
Solubility (25C) * In vitro DMSO 76 mg/mL (199.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol 33 mg/mL (86.53 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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