LAQ824 (NVP-LAQ824)Catalog No. A10516

Quick Overview

LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
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LAQ824 (NVP-LAQ824)

Product Information
Catalog Num A10516
M. Wt 379.5
Formula C22H25N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 404951-53-7
Synonyms NVP-LAQ824, Dacinostat, LAQ-824
Chemical Name (E)-N-hydroxy-3-[4-[[2-hydroxyethyl-[2-(1H-indol-3-yl)ethyl]amino]meth yl]phenyl]prop-2-enamide
SMILES Code C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)/C=C/C(=O)NO

Biological activity
Introduction
LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Targets
HDAC
32 nM
Solubility
Solubility (25C) * In vitro DMSO 76 mg/mL (200.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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