Lenalidomide (CC-5013)Catalog No. A10522

Quick Overview

Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
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Lenalidomide (CC-5013)

Product Information
Catalog Num A10522
M. Wt 259.3
Formula C13H13N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 191732-72-6
Synonyms CC-5013, Revlimid
Chemical Name (RS)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
SMILES Code C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

Biological activity
Introduction
Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
Solubility
Solubility (25C) * In vitro DMSO 52 mg/mL (200.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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