MK-1775Catalog No. A10599

Quick Overview

MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.
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MK-1775

Product Information
Catalog Num A10599
M. Wt 500.6
Formula C27H32N8O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 955365-80-7
Synonyms MK1775,MK 1775
Chemical Name 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one
SMILES Code CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

Biological activity
Introduction
MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.
Targets
Wee1 (Cell-free assay)
5.2 nM
Solubility
Solubility (25C) * In vitro DMSO 80 mg/mL (159.8 mM)
Water 0.0001 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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