NVP-ADW742Catalog No. A10658

Quick Overview

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
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NVP-ADW742

Product Information
Catalog Num A10658
M. Wt 453.6
Formula C28H31N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 475488-23-4
Synonyms NVPADW742, ADW742, ADW-742, GSK 552602A
Chemical Name 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
SMILES Code C1CCN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6

Biological activity
Introduction
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
Targets
IGF-1R
0.17 μM
Solubility
Solubility (25C)* In vitro DMSO 10 mg/mL heating (22.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (6.61 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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