PD153035 (HCl salt)Catalog No. A10702

Quick Overview

PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
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PD153035 (HCl salt)

Product Information
Catalog Num A10702
M. Wt 396.7
Formula C16H14BrN3O2.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183322-45-4
Synonyms ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271, PD-153035
Chemical Name N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride
SMILES Code COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl

Biological activity
Introduction
PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
Targets
EGFR (Cell-free assay) EGFR (Cell-free assay)
5.2 pM(Ki)5.2 pM(Ki)
Solubility
Solubility (25C) * In vitro DMSO 0.5 mg/mL (1.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% Propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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