PirarubicinCatalog No. A10735

Quick Overview

Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication
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Pirarubicin

Product Information
Catalog Num A10735
M. Wt 627.64
Formula C32H37NO12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 72496-41-4
Synonyms THP-Adriamycin
Chemical Name (7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
SMILES Code C[[email protected]@H]1[[email protected]@H]([[email protected]@H](C[[email protected]](O1)OC2C[[email protected]](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O[[email protected]@H]6CCCCO6

Biological activity
Introduction
Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication
Targets
Topo II
Solubility
Solubility (25C)* In vitro DMSO 7 mg/mL (11.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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