LY2603618 (IC-83)Catalog No. A11036

Quick Overview

LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.
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LY2603618 (IC-83)

Product Information
Catalog Num A11036
M. Wt 436.3
Formula C18H22BrN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 911222-45-2
Synonyms LY-2603618
Chemical Name N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)urea
SMILES Code CC1=CC(=C(C=C1Br)NC(=O)NC2=NC=C(N=C2)C)OC[[email protected]@H]3CNCCO3

Biological activity
Introduction
LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.
Targets
Chk1 (Cell-free assay)
Solubility
Solubility (25C) * In vitro DMSO 13 mg/mL (29.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 2% DMSO, 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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