SB 415286 Catalog No. A11061
Quick Overview
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
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Product Information
Catalog Num | A11061 |
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M. Wt | 359.7 |
Formula | C16H10ClN3O5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 264218-23-7 |
Synonyms | SB-415286, SB415286 |
Chemical Name | 3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione |
SMILES Code | C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-] |
Biological activity
Introduction |
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM. | ||||||||||
Targets |
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Solubility
Solubility (25C)* | In vitro | DMSO | 72 mg/mL (200.15 mM) |
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Water | <1 mg/mL (<1 mM) | ||
Ethanol | 72 mg/mL (200.15 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Return Policy | Contact information |
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