SKF 86002 DihydrochlorideCatalog No. A11101

Quick Overview

SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).
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SKF 86002 Dihydrochloride

Product Information
Catalog Num A11101
M. Wt 370.27
Formula C16H12FN3S.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 116339-68-5
Synonyms SKF86002 Dihydrochloride
Chemical Name 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride
SMILES Code C1CSC2=NC(=C(N21)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl.Cl

Biological activity
Introduction
SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).
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High Purity Kinase Inhibitors on Signaling Pathways

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