PHA-767491Catalog No. A11164

Quick Overview

PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

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PHA-767491

Product Information
Catalog Num A11164
M. Wt 213.24
Formula C12H11N3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 845714-00-3
Synonyms PHA767491
Chemical Name 1,5,6,7-Tetrahydro-2-(4-pyridinyl)- 4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
SMILES Code C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3

Biological activity
Introduction

PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.

Solubility
Solubility (25C) * In vitro DMSO 24 mg/mL (112.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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