KX2-391Catalog No. A11177

Quick Overview

KX2-391 is a novel non-ATP competitive substrate-pocket directed SRC inhibitor.

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KX2-391

Product Information
Catalog Num A11177
M. Wt 431.53
Formula C26H29N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 897016-82-9
Synonyms KX2391
Chemical Name (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone
SMILES Code C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4

Biological activity
Introduction

KX2-391 is a novel non-ATP competitive substrate-pocket directed SRC inhibitor.

Targets
Src (HuH7) (Cell-free assay) Src (PLC/PRF/5) (Cell-free assay) Src (Hep 3B) (Cell-free assay) Src (Hep G2) (Cell-free assay)
9 nM(GI50)13 nM(GI50)26 nM(GI50)60 nM(GI50)
Solubility
Solubility (25C) * In vitro DMSO 86 mg/mL (199.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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