ADX-47273Catalog No. A11181

Quick Overview

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

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ADX-47273

Product Information
Catalog Num A11181
M. Wt 369.36
Formula C20H17F2N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 851881-60-2
Synonyms ADX47273
Chemical Name (S)-(4-fluorophenyl)-(3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]piperidin-1-yl)methanone
SMILES Code C1C[[email protected]@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F

Biological activity
Introduction

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

Targets
mGlu5
0.17 μM(EC50)
Solubility
Solubility (25C) * In vitro DMSO 74 mg/mL (200.34 mM)
Water <1 mg/mL (<1 mM)
Ethanol 30 mg/mL (81.22 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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