WAY-600Catalog No. A11188

Quick Overview

WAY-600 is a single digit nanomolar inhibitor of the mTOR kinases, with significant selectivity for these enzymes over phosphatidylinositol 3-kinase (PI3K) isofoms (>100-fold).

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WAY-600

Product Information
Catalog Num A11188
M. Wt 494.59
Formula C28H30N8O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1062159-35-6
Synonyms WAY600
Chemical Name 6-(1H-Indol-5-yl)-4-(4-morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine
SMILES Code C1CN(CCC1N2C3=C(C=N2)C(=NC(=N3)C4=CC5=C(C=C4)NC=C5)N6CCOCC6)CC7=CN=CC=C7

Biological activity
Introduction

WAY-600 is a single digit nanomolar inhibitor of the mTOR kinases, with significant selectivity for these enzymes over phosphatidylinositol 3-kinase (PI3K) isofoms (>100-fold).

Solubility
Solubility (25C)* In vitro DMSO 22 mg/mL (44.48 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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