PNU-120596Catalog No. A11203

Quick Overview

PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
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PNU-120596

Product Information
Catalog Num A11203
M. Wt 311.72
Formula C13H14ClN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501925-31-1
Synonyms PNU120596
Chemical Name N-(5-Chloro-2,4-dimethoxyphenyl)-N'- (5-methyl-3-isoxazolyl)-urea
SMILES Code CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

Biological activity
Introduction
PNU-120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors.
Targets
α7 nAChR
216 nM(EC50)
Solubility
Solubility (25C) * In vitro DMSO 62 mg/mL (198.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (3.2 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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