Exatecan mesylateCatalog No. A11231

Quick Overview

Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
Products are for laboratory research use only. Not for human use. We do not sell to patients.

Exatecan mesylate

Product Information
Catalog Num A11231
M. Wt 531.6
Formula C25H26FN3O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 171335-80-1
Synonyms DX 8951, DX8951
Chemical Name (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione mesylate
SMILES Code CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C5[[email protected]](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O

Biological activity
Introduction
Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
Return Policy Contact information
Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems.

>>This offer is only valid for products purchased directly from Adooq and its authorized distributors.

>>Prior to returning any items, please contact the Customer Service ([email protected]) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased.


Website: www.adooq.com
Order: [email protected]
Phone:
(866)930-6790 (US & Canada)
+1-323-389-9269 (Outside of US & CAN)
Fax:
(866)333-9607 (US & Canada)
+1-323-606-8156 (Outside of US & CAN)
Support:
[email protected]

High Purity Kinase Inhibitors on Signaling Pathways

Copyright© 2006-2017 Adooq BioScience LLC, All Rights Reserved.
4000 Barranca Parkway, Suite 250, Irvine, CA 92604 USA. Tel: 855-930-6790