TAK-438 (vonoprazan)Catalog No. A11239

Quick Overview

TAK-438 is a novel potassium-competitive acid blocker.
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TAK-438 (vonoprazan)

Product Information
Catalog Num A11239
M. Wt 461.5
Formula C21H20FN3O6S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1260141-27-2
Synonyms TAK438
Chemical Name 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate
SMILES Code CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O

Biological activity
Introduction
TAK-438 is a novel potassium-competitive acid blocker.
Targets
H+/K+-ATPase
19 nM
Solubility
Solubility (25C) * In vitro DMSO 62 mg/mL (134.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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