MLN4924 (Pevonedistat)Catalog No. A11260

Quick Overview

NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.
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MLN4924 (Pevonedistat)

Product Information
Catalog Num A11260
M. Wt 443.5
Formula C21H25N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 905579-51-3
Synonyms MLN-4924
Chemical Name Sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl ester
SMILES Code C1CC2=CC=CC=C2[[email protected]]1NC3=NC=NC4=C3C=CN4[C@@H]5C[[email protected]]([[email protected]](C5)O)COS(=O)(=O)N

Biological activity
Introduction
NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.
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