PX-866Catalog No. A11261

Quick Overview

PX-866 is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity.
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PX-866

Product Information
Catalog Num A11261
M. Wt 525.2
Formula C29H35NO8
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 502632-66-8
Synonyms PX866
Chemical Name (4S,4aR,5R,6aS,9aR,E)-1-((diallylamino)methylene)-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-2,7,10-trioxo-1,2,4,4a,5,6,6a,7,8,9,9a,10-dodecahydroindeno[4,5-h]isochromen-5-yl acetate
SMILES Code O=C(/C1=C\N(CC=C)?CC=C)?O[[email protected]]?(COC)?[[email protected]@]?2(C)?C1=C(O)?C(C3=C2[[email protected]]?(OC(C)?=O)?C[[email protected]@]?4(C)?[[email protected]@]?3([H]?)?CCC4=O)?=O

Biological activity
Introduction
PX-866 is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity.
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High Purity Kinase Inhibitors on Signaling Pathways

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