A-443654Catalog No. A11287

Quick Overview

A-443654, a specific Akt inhibitor with Ki value of 160 pM, interferes with mitotic progression and bipolar spindle formation.
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A-443654

Product Information
Catalog Num A11287
M. Wt 397.5
Formula C24H23N5O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 552325-16-3
Synonyms A443654
Chemical Name (S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine
SMILES Code CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OC[[email protected]](CC4=CNC5=CC=CC=C54)N

Biological activity
Introduction
A-443654, a specific Akt inhibitor with Ki value of 160 pM, interferes with mitotic progression and bipolar spindle formation.
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High Purity Kinase Inhibitors on Signaling Pathways

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