Adarotene (ST1926)Catalog No. A11298

Quick Overview

Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its glucuronide metabolite in the urines.
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Adarotene (ST1926)

Product Information
Catalog Num A11298
M. Wt 374.5
Formula C25H26O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 496868-77-0
Synonyms ST 1926, ST1926
Chemical Name (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
SMILES Code C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC=C(C=C5)/C=C/C(=O)O)O

Biological activity
Introduction
Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its glucuronide metabolite in the urines.
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