Baricitinib (LY3009104)Catalog No. A11329
Quick Overview
Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).
Products are for laboratory research use only. Not for human use. We do not sell to patients.
Product Information
| Catalog Num | A11329 |
|---|---|
| M. Wt | 371.4 |
| Formula | C16H17N7O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1187594-09-7 |
| Synonyms | INCB28050, LY3009104 |
| Chemical Name | 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile |
| SMILES Code | CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
Biological activity
Introduction |
Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM). | ||||||||||||||
Targets |
|
Solubility
| Solubility (25C) * | In vitro | DMSO | 74 mg/mL (199.23 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Return Policy | Contact information |
| Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems. >>This offer is only valid for products purchased directly from Adooq and its authorized distributors. >>Prior to returning any items, please contact the Customer Service (sales@adooq.com) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased. |
Website: www.adooq.com Order: sales@adooq.com Phone: (866)930-6790 (US & Canada) +1-323-389-9269 (Outside of US & CAN) Fax: (866)333-9607 (US & Canada) +1-323-606-8156 (Outside of US & CAN) Support: support@adooq.com |