MK-8033Catalog No. A11489

Quick Overview

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.
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MK-8033

Product Information
Catalog Num A11489
M. Wt 471.53
Formula C25H21N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1001917-37-8
Synonyms MK 8033, MK8033
Chemical Name 1-[2-(1-methylpyrazol-4-yl)-11-oxobenzo[1,2]cyclohepta[2,4-b]pyridin-9-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide
SMILES Code CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)C(=O)C3=C2

Biological activity
Introduction
MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.
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