VS-5584 Catalog No. A12480

Quick Overview

VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
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VS-5584

Product Information
Catalog Num A12480
M. Wt 354.41
Formula C17H22N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1246560-33-7
Synonyms SB2343, VS5584, SB-2343, SB 2343
Chemical Name N/A
SMILES Code CC1=NC2=C(N=C(N=C2N1C(C)C)N3CCOCC3)C4=CN=C(N=C4)N

Biological activity
Introduction
VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Targets
PI3Kα PI3Kδ PI3Kγ mTOR PI3Kβ
2.6 nM2.7 nM3.0 nM3.4 nM21 nM
Solubility
Solubility (25C) * In vitro DMSO 71 mg/mL (200.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (8.46 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems.

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>>Prior to returning any items, please contact the Customer Service ([email protected]) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased.


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High Purity Kinase Inhibitors on Signaling Pathways

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