Kobe2602Catalog No. A12578

Quick Overview

Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.
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Kobe2602

Product Information
Catalog Num A12578
M. Wt 419.31
Formula C14H9F4N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 454453-49-7
Synonyms Kobe-2602
Chemical Name 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide
SMILES Code C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F

Biological activity
Introduction
Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.
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High Purity Kinase Inhibitors on Signaling Pathways

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