SR 3677 dihydrochlorideCatalog No. A12674

Quick Overview

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
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SR 3677 dihydrochloride

Product Information
Catalog Num A12674
M. Wt 481.37
Formula C22H24N4O4.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1072959-67-1
Synonyms SR3677, SR-3677
Chemical Name N-{2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl}-2,3-dihydro-1,4-benzodioxine-2-carboxamide hydrochloride
SMILES Code CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3

Biological activity
Introduction
SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
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High Purity Kinase Inhibitors on Signaling Pathways

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