GDC-0032 (Taselisib)Catalog No. A12831

Quick Overview

GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.
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GDC-0032 (Taselisib)

Product Information
Catalog Num A12831
M. Wt 460.53
Formula C24H28N8O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1282512-48-4
Synonyms GDC 0032, GDC0032
Chemical Name
SMILES Code CC1=NN(C(=N1)C2=CN3CCOC4=C(C3=N2)C=CC(=C4)C5=CN(N=C5)C(C)(C)C(=O)N)C(C)C

Biological activity
Introduction
GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.
Targets
Target Value
PI3Kδki: 0.12nM
PI3Kαki: 0.29nM
PI3Kγki: 0.97nM
PI3Kβki: 9.1nM
C2βIC50: 292nM
hVps34IC50: 374nM
mTORki: 1.2μM
DNA-PKIC50: >4.8μM
C2αIC50: >10μM
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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