ZM-241385Catalog No. A13517

Quick Overview

ZM-241385 is a potent and highly selective Adenosine A2A-R antagonist, with a pA2 of 9.02 for Adenosine A2A-R in cardiac vasculature and selectivities of 1000, 91 and 500,000 over Adenosine A1-R, Adenosine A2B-R and Adenosine A3-R sites, respectively.
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ZM-241385

Product Information
Catalog Num A13517
M. Wt 337.34
Formula C16H15N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 139180-30-6
Synonyms ZM241385, ZM 241385
Chemical Name 4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol
SMILES Code C1=COC(=C1)C2=NN3C(=NC(=NC3=N2)NCCC4=CC=C(C=C4)O)N

Biological activity
Introduction
ZM-241385 is a potent and highly selective Adenosine A2A-R antagonist, with a pA2 of 9.02 for Adenosine A2A-R in cardiac vasculature and selectivities of 1000, 91 and 500,000 over Adenosine A1-R, Adenosine A2B-R and Adenosine A3-R sites, respectively.
Targets
adenosine A2A receptor
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