OTX015Catalog No. A13890

Quick Overview

OTX015 is an orally bioavailable, small molecule inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10-19 nM).
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OTX015

Product Information
Catalog Num A13890
M. Wt 491.99
Formula C25H22ClN5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 202590-98-5
Synonyms OTX 015, OTX-015
Chemical Name (6S)-?4-?(4-?chlorophenyl)-?N-?(4-?hydroxyphenyl)-?2,?3,?9-?trimethyl-?6H-?thieno[3,?2-?f][1,?2,?4]triazolo[4,?3-?a][1,?4]diazepine-?6-?acetamide
SMILES Code CC1=C(SC2=C1C(=N[[email protected]](C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C

Biological activity
Introduction
OTX015 is an orally bioavailable, small molecule inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10-19 nM).
Targets
BRDs (Cell-free assay)
10-19 nM(EC50)
Solubility
Solubility (25C)* In vitro DMSO 98 mg/mL (199.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol 98 mg/mL (199.19 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems.

>>This offer is only valid for products purchased directly from Adooq and its authorized distributors.

>>Prior to returning any items, please contact the Customer Service ([email protected]) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased.


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High Purity Kinase Inhibitors on Signaling Pathways

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