GSK 525768ACatalog No. A14134

Quick Overview

GSK 525768A is the enantiomer compound of GSK 525762A, which is a potent small molecule inhibitor that disrupt the function of the BET family of bromodomains (Brd2, Brd3, and Brd4); GSK 525768A has NO activity towards BET.
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GSK 525768A

Product Information
Catalog Num A14134
M. Wt 423.9
Formula C22H22ClN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1260530-25-3
Synonyms GSK525768A, GSK-525768A
Chemical Name 2-[(4R)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
SMILES Code CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C

Biological activity
Introduction
GSK 525768A is the enantiomer compound of GSK 525762A, which is a potent small molecule inhibitor that disrupt the function of the BET family of bromodomains (Brd2, Brd3, and Brd4); GSK 525768A has NO activity towards BET.
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High Purity Kinase Inhibitors on Signaling Pathways

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