CYT387 sulfate saltCatalog No. A15056

Quick Overview

CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
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CYT387 sulfate salt

Product Information
Catalog Num A15056
M. Wt 610.62
Formula C23H26N6O10S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1056636-06-6
Synonyms CYT-387 sulfate, CYT 387 sulfate, momelotinib sulfate
Chemical Name N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide; sulfuric acid
SMILES Code C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O

Biological activity
Introduction
CYT387 sulfate salt is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
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High Purity Kinase Inhibitors on Signaling Pathways

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