MK-3207Catalog No. A15165

Quick Overview

MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.
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MK-3207

Product Information
Catalog Num A15165
M. Wt 557.59
Formula C31H29F2N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957118-49-9
Synonyms MK3207, MK 3207
Chemical Name (8R)-8-(3,5-Difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide
SMILES Code C1CCC2(C1)C(=O)N(C(CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(CC6(C5)C7=C(NC6=O)N=CC=C7)C=C4

Biological activity
Introduction
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.
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High Purity Kinase Inhibitors on Signaling Pathways

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