AZD6738Catalog No. A15794

Quick Overview

AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.
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AZD6738

Product Information
Catalog Num A15794
M. Wt 412.51
Formula C20H24N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1352226-88-0
Synonyms AZD-6738, AZD 6738
Chemical Name (R)-imino(methyl)(1-(6-((R)-3-methylmorpholino)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)cyclopropyl)-l6-sulfanone
SMILES Code C[[email protected]]1N(C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(C5([[email protected]](=O)(C)=N)CC5)=C2)CCOC1

Biological activity
Introduction
AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.
Targets
ATR
1 nM
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High Purity Kinase Inhibitors on Signaling Pathways

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