ACP-196 (Acalabrutinib)Catalog No. A15824

Quick Overview

ACP-196 is an orally available inhibitor of Bruton‘s tyrosine kinase (BTK) with potential antineoplastic activity. It inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.
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ACP-196 (Acalabrutinib)

Product Information
Catalog Num A15824
M. Wt 465.52
Formula C26H23N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1420477-60-6
Synonyms Acalabrutinib, ACP196, ACP 196
Chemical Name (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
SMILES Code CC#CC(=O)N1CCCC1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5

Biological activity
Introduction
ACP-196 is an orally available inhibitor of Bruton‘s tyrosine kinase (BTK) with potential antineoplastic activity. It inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.
Targets
BTK
3nM
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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