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DDR1-IN-1

DDR1 receptor inhibitor

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Catalog No. A13985

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
DDR1-IN-1 5mg A13985-5
$100.00
DDR1-IN-1 10mg A13985-10
$175.00
DDR1-IN-1 25mg A13985-25
$350.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM).

DDR1-IN-1

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Chemical Information

Catalog Num A13985
Actions Inhibitor
M. Wt 552.59
Formula C30H31F3N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1449685-96-4
Synonyms N/A
SMILES code CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F
Chemical Name 4-[(4-ethylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(2-oxo-1,3-dihydroindol-5-yl)oxy]phenyl]-3-(trifluoromethyl)benzamide

Biological Activity

Description
DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM).
Targets
DDR1 DDR2
105 nM413 nM

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