Delamanid (OPC-67683)

Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
Grouped product items
Product Name Price Stock Qty
Delamanid 5mg
$40.00
In stock
Delamanid 10mg
$75.00
In stock
Delamanid 25mg
$150.00
In stock
Delamanid 50mg
$280.00
In stock
Delamanid 100mg
$420.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Delamanid (OPC-67683) has been cited by 3 publications
  • Thanh Quang Nguyen, .et al. , Antimicrob Agents Chemother, 2022, Dec 20;66(12):e0044822 PMID: 36321819
  • Meikle V, .et al. , Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480
  • World Health Organization, .et al. , World Health Organization, 2018, WHO/CDS/TB/2018.24
  • Biological Activity
    Discription Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
    Product Information
    Catalog Num A12864
    Formula C25H25F3N4O6
    Molecular Weight 534.48
    CAS Number 681492-22-8
    SMILES C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 85 mg/mL (159.03 mM) Need ultrasonic
    Water Insoluble
    Ethanol 2 mg/mL
    In vivo 2.5 mg/mL (4.68 mM) Need ultrasonic 10% DMSO 40% PEG300 5% Tween-80 45% Saline
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.71 mL 93.55 mL 187.1 mL
    0.5 mM 3.74 mL 18.71 mL 37.42 mL
    1 mM 1.87 mL 9.35 mL 18.71 mL
    5 mM 0.37 mL 1.87 mL 3.74 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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