DNA alkylator



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Catalog No. Product Name Application Product Information
A10124 SALE

Bendamustine HCl (SDX-105)

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Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.

A10059

Altretamine

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Altretamine is classified as an alkylating antineoplastic agent.This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation.
A11635 SALE

Cyclophosphamide monohydrate

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Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations.
A13473

Uramustine

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Uramustine is a chemotherapy drug which belongs to the class of alkylating agents.
A15162

Miriplatin hydrate

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Miriplatin hydrate is a lipophilic platinum complex containing myristates as leaving groups, and can be easily suspended in ethyl esters of iodized fatty acids obtained from poppy seed oil.
A15269

VAL-083

bi-functional alkylating agent
VAL-083 is a bi-functional alkylating agent; inhibit U251 and SF188 cell growth in monolayer better than TMZ and caused apoptosis.
A15344 SALE

Melphalan

DNA alkylating agent
Melphalan is a cytotoxic drug used to treat multiple myeloma. Phenylamine derivative of mechorethamine.
A10930

Thiotepa

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Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity.

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