DUB



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Catalog No. Product Name Application Product Information
A13352

HBX 41108

USP 7 inhibitor
HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM).
A13209

IU1

Usp14 inhibitor
IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).
A12715

LDN-57444

UCH-L1 Inhibitor
LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1.
A15391

NSC 687852

DUB inhibitor
NSC 687852 is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), two proteasome-associated DUBs.
A13277

P005091

DUB/USP7 Inhibitor
P005091 is a selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 uM).
A13190

PR-619

DUB inhibitor
PR-619 is a cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs).
A10988

WP1130 ( Degrasyn )

DUB/Bcr/ABL Inhibitor
WP1130 (Degrasyn) is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia (CML) cells.

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