Epirubicin HCl

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Catalog No. A10345

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Product Name Catalog No. Price Qty
Epirubicin Hydrochloride 5mg A10345-5

Regular Price: $40.00

Special Price: $34.00

Epirubicin Hydrochloride 10mg A10345-10

Regular Price: $70.00

Special Price: $59.50

Epirubicin Hydrochloride 50mg A10345-50

Regular Price: $200.00

Special Price: $170.00

Epirubicin Hydrochloride 100mg A10345-100

Regular Price: $320.00

Special Price: $272.00

Epirubicin Hydrochloride 10mM * 1mL in DMSO A10345-10mM-D

Regular Price: $60.00

Special Price: $51.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Epirubicin is a cell-permeable anthracycline antitumor antibiotic. It is a stereoisomer(4′-epi-isomer) of doxorubicin that exhibits reduced cardiotoxicity. It is used to inhibit topoisomerase II and DNA helicase activity.

Epirubicin HCl

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Chemical Information

Catalog Num A10345
Actions N/A
M. Wt 580
Formula C27H30ClNO11
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 56390-09-1
Synonyms Ellence, Pharmorubicin, Epirubicin Ebewe
SMILES code C[[email protected]]1[[email protected]@H]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Chemical Name (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride

Biological Activity

Description
Epirubicin is a cell-permeable anthracycline antitumor antibiotic. It is a stereoisomer(4′-epi-isomer) of doxorubicin that exhibits reduced cardiotoxicity. It is used to inhibit topoisomerase II and DNA helicase activity.
Targets
Topoisomerase (Cell-free assay)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (172.41 mM)
Water 100 mg/mL heating (172.41 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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