HIV Integrase

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  1. HIV-1 integrase inhibitor

    BMS-707035 is an HIV-1 integrase (IN) inhibitor. HIV-1 integrase (IN) represents a therapeutically advantageous viral target to treat HIV/AIDS in the clinic.

  2. HIV integrase inhibitor

    Elvitegravir (GS-9137) is a potent inhibitor of the strand-transfer step of integration mediated by human immunodeficiency virus type 1 (HIV-1) integrase.
  3. HIV-1 integrase inhibitor

    Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.
  4. ICN1229, ICN-1229, ICN 1229

    Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.
  5. HIV integrase inhibitor

    S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones.
  6. HIV integrase inhibitor

    MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection.
  7. HIV-1 integrase inhibitor

    HIV-1 integrase inhibitor is uesful for anti-HIV.
  8. HIV-1 integrase inhibitor

    HIV-1 integrase inhibitor 2, in the treatment of human immunodeficiency virus (HIV) infection.
  9. HIV Protease Inhibitor

    Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.
  10. HIV Integrase Inhibitor

    GSK1265744 (GSK744) is a potential inhibitor of HIV integrase with IC50 value of 3 nM
  11. HIV integrase inhibitor

    GSK744 is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.
  12. HIV integrase inhibitor

    BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of >90 μM.
  13. HIV integrase inhibitor

    Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
  14. HIV-1 integrase Inhibitor

    Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile.
  15. INST inhibitor

    HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
  16. INST inhibitor

    HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
  17. integrase inhibitor

    Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection.
  18. integrase (IN) inhibitor

    Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.

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